الفهرس | Only 14 pages are availabe for public view |
Abstract This thesis includes three chapters in addition to chapter of introduction No.1: In chapter 2, AuNPs were successfully biosynthesized using edible mushroom Pleurotus ostreatus extracellular filtrate as a reducing and capping agents. AuNPs have been characterized by UV-vis spectroscopy, TEM, XRD and FTIR. The obtained results confirmed the crystalline nature of AuNPs and morphological studies showed spherical shape of AuNPs with size ranging from 10-30 nm. Zeta potential -24.0 mV for AuNPs reveal moderate stability. Optimization of the chemical and physical parameters achieved to obtain high yield of gold nanoparticles. Further, biosynthesized AuNPs enhanced anticancer and synergist antimicrobial activity than the commercial AuNPs. In chapter3, Biosynthesis of AgNPs has many advantages such as economic viability and easy scale up. Applications of nanoparticles in medical and other fields make this method potentially use for the large-scale synthesis of other inorganic nanomaterials. Narrow size distribution and small Nano size AgNPs also offer advantages for self-assembled monolayer formation and enhanced surface area. Our biosynthesized Silver Nanoparticles solution is biologically well suited and has the potential Antibacterial activity also can be used with other pharmaceutical compound to enhance their activity. In chapter4,We fabricated 4E phage color sensor for detection VOCs of different type of bacteria, our sensor is eco-friendly, cheap and can used many times (not disposable). Further we can develop this sensor as point-of-care for medical diagnosis of H.Pylori infection among breath of patients and other lung cancer screening. |