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Abstract The cornea is a transparent, avascular tissue, which covers the anterior one-sixth of the eye, the central portion of the anterior corneal surface acts as the sphero cylindrical convex mirror. Corneal refractive surgery aims to alter the refractive power of the cornea by changing its shape to decrease dependency on eyeglasses or contact lenses. Keratorefractive procedures include incisional, Surface Ablation, LASIK, Femto LASIK, Refractive lenticule extraction, Intrastromal Corneal Ring Segments. Corneal refractive surgery mostly acts on the anterior cornea, Corneal curvature and thickness are remodeled for inducing refractive changes, Also it altered the corneal biomechanical properties. Corneal thickness is an important factor in determining whether the patient is suitable for refractive surgery and identifying the optimal refractive procedure, Corneal thicknesses are measured by, Pentacam, anterior segment optical coherence tomography (AS-OCT), ultrasound pachymetry, Orbscan measurements, and noncontact specular microscopy. IOP measurement is important parameters in the glaucoma classification, diagnosis, follow-up and treatment of and ocular hypertension. The Corneal thickness is the local factors that influence the measurements. IOP measurement by several methods as Goldmann Applanation Tonometer (GAT) , The Perkins applanation tonometer, Non-contact air puff tonometer (NCT) , Tono-pen (TP) hand tonometry, The rebound tonometer (RT; I-Care), The Diaton tonometer, Dynamic contour tonometry (DCT), Pneumatonometer, Ocular Response Analyzer (ORA) , Corvis ST (CST), Ocuton S. Corneal refractive surgery ablates of the corneal tissue that induces changes in the corneal curvature, central corneal thickness (CCT), and cornealSummary - 113 - rigidity, These changes alter the postoperative IOP and make the IOP assessment is unreliable. Corneal refractive surgery decrease IOP due to the quantity of tissue removed, IOP reduction after Corneal refractive surgery was significant and correlated with preoperative IOP, CCT, and The spherical equivalent of the attempted correction. The main objective is to study the role of central corneal thickness in the estimation of Intraocular pressure after Corneal refractive surgery , One hundred and fifty eyes of seventy-five patients diagnosed clinically to have refractive error were selected. Their ages ranged from 19-42 years. 50 eyes operated using the Femto-LASIK group[1], 50 eyes operated using the Lasik group [2]. and 50 eyes operated using the PRK group[3]. Central corneal thickness was measured for all patients before and after the operation. IOP measurement was performed for all patients before and after the operation one, three and six month Overall, measured IOP is underestimated after Corneal refractive surgery, There are highly significant decreases in IOP postoperatively and in follow up period among Femto LASIK, LASIK groups at 1,3 and 6 months. In the PRK group there is a highly significant decrease in IOP in the follow-up period after 3 and 6 months but, little significant difference after one month of the operation. |