الفهرس 
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Abstract
Nowadays, obesity becomes the major public concern, and all actions directed toward how to reduce obesity and encourage people to become fit and healthy. In addition, obesity management is essential to reduce co morbidities and increase the quality of life. Obesity is also associated with decrease in male testosterone levels. Unpleasant effects on energy expenditure and fat oxidation were demonstrated in elderly males suffering from androgen deprivation.
Exercise continues to be an effective tool to study the body’s response to metabolic stress and provides an alternative choice to several drugs besides its role in improving serum testosterone. Additionally, testosterone supplementation presents affirmative effects in glycemic and lipid control, insulin resistance and visceral adiposity in hypogonadal men suffering from impaired glucose tolerance and lipid profile.
This work is designed to compare the protective effects of moderate treadmill exercise and/or testosterone replacement on lipid metabolism and oxidative status in an orchidectomized male Sprague dawely rat model.
For this purpose, 60 adult male Sprague dawely rats were divided into 6 equal groups (10 for each) as follow:
group (1): SHAM operated sedentary; rats were kept in the same conditions as the experimental groups, but not subjected to any procedure and intraperitoneally administered with sesame oil.