الفهرس 
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Abstract
The most common form of congenital heart disease in childhood is the VSD, occurring in 50% of all children with congenital heart disease and in 20% as an isolated lesion.
The size of the VSD, the pressure in the right and left ventricular chambers, and the pulmonary resistance are factors that influence the hemodynamic significance of VSDs.
Left-to-right shunting in VSDs generally increases pulmonary arterial blood flow and pulmonary venous return to the left heart. This pathophysiologic sequels may result in volume overload of the left atrium and left ventricle, and subsequent left ventricular enlargement, mitral annular dilation, mitral regurgitation, and consequent left atrial enlargement to allow for the homeostatic balance of left atrial pressure.
The aim of this study was to evaluate improvement in LV dimensions and LV function after surgical closure of VSD in pediatric age group.
This prospective study included 30 children with isolated congenital VSD who met inclusion criteria. All patients were subjected to: full history taking, clinical examination, complete echocardiographic analysis for the VSD, LV dimensions and degree of MR.
All patients were brought for follow up visits at 3 and 6 months where TTE was reported for: adequacy of VSD closure, assessment of LVEDD, LVESD and degree of MR.
Mean age of patients was 22.9 +/-29 months. About 17 were females, and 13 were males. Sixty eight percent had perimembranous VSD, 13% had muscular VSD, 10% had inlet VSD and 10 % had outlet VSD. Eighty percent of our patients had no MR, 13 % had mild MR, 7% had moderate MR. There was significant increase in ejection fraction in postoperative follow-up echocardiography. There was significant progressive reduction in left ventricular end diastolic diameter and end systolic diameter in 3month and 6 months follow up echo. Degree of mitral regurgitation did not significantly decreased post- surgery