الفهرس 
AcknowledgementsOnly 14 pages are availabe for public view
 |  | from | 72 |  |  |
| | | from | 72 | | |
Abstract
With recent advances in our knowledge of corneal physiology, coupled with the development and increasing availability of the specular microscope as a clinical instrument, valid observations relating the morphologic appearance of the corneal endothelium to its functional capacity are within our reach.
Specular microscopy can provide a non invasive morphologic analysis of the corneal endothelial cell layer from subjects enrolled in clinical trials. The analysis provides a measure of the endothelial cell physiologic reserve from aging, ocular surgical procedures, pharmaceutical exposure, and general health of the corneal endothelium.
Our thesis aims to study the corneal endothelium by specular microscopy in middle aged patients with cataract.
We evaluated a 500 eyes of 500 patients (244 females and 256 males) with cataract whose ages were between 40 and 60 (mean, 51.99 ± 7.32) that accepted to participate in our study voluntarily after they were informed about the procedures within the scope of the study in Sohag ophthalmic investigation center.
Non-contact Topcon specular microscopy was performed in the studied eyes with cataract. Endothelial cell density (ECD), coefficient of variation (CV) in cell size, hexagonality of cells (HEX), and number of cells (N) were measured.
The results of the present study revealed that the mean of Endothelial cell density is 2835.29 ± 476.01 cell/mm2, coefficient of variation in cell size is 37.78 ± 9.60 %, hexagonality of cells is 50.16 ± 9.85 % and number of cell is 158.39 ± 55. 86 cells.Our results in this study show marked similarities with other data reported by previous researchers.