الفهرس | Only 14 pages are availabe for public view |
Abstract Organophosphorus compounds are most commonly used as insecticides in Egypt. There are more than 40 different types known and used today either individually or in mixed forms between more than one type. This study aims to detect various types of organophosphorus insecticides from poisoned patients admitted to Poison Control Center, Ain Shams University (PCCASU). Sixty acutely intoxicated patients and ten workers chronically exposed to OPI were admitted to (PCCASU), Ten healthy adults served as control .The study found that 15 out of 60(26%) acute patients were from age group (10-20) and 15 out of 60 (26%) were from age group (30-40). 46% of the total number of patients (n=70) were exposed due to suicidal attempts, 40% were accidentally exposed and 14% were due to occupational hazard. 56% of the studied cases were from urban residents. 23% of total numbers of suicidal cases were unemployed, where 50% of them are from low socioeconomic status. The study detected 7 different OPI (Malathion, Dimethoate, Chloropyrofois, Phenthoate, Prothiphos, Profenfos, and Ethion). 45.7% of total detected where combination of more than one type (mixed form). 54.3% were intoxicated due to a single form of OPI of which the Malathion showed highest prevalence with 17.2%, While Chloropyrofis showed highest frequency (55.7%) of cases in both mixed and single forms of OPI. Blood random glucose level significantly increased in deceased and severe groups in comparison to control, while serum sodium level showed no significant difference. Potassium level significantly decreased in severe and moderate group. Amylase was significantly high in severe and deceased group, while urea slightly elevated in sever group only. Creatinine level significantly high in severe group. Significant increase on both AST, ALT was also noticed. The study also revealed that pseudocholinestrase level was decreased significantly in deceased, severe and moderate group with no significant difference among three previous groups. |