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العنوان
Impact of Cerebrovascular Stroke Site On Degree of Erectile function,Total testosterone and Prolactin hormoneLevel /
المؤلف
Mahdy, Doaa Ahmed Sayed.
هيئة الاعداد
باحث / دعاء أحمد سيد مهدي
مشرف / عماد الدين كمال علي
مناقش / رشاد محمود مصطفى
مناقش / على محمد عبد الرحمن
الموضوع
Cerebral stroke.
تاريخ النشر
2019.
عدد الصفحات
92 P. :
الفهرس
Only 14 pages are availabe for public view

from 92

from 92

Abstract

Erectile Dysfunction(ED) is a common problem in Cerebrovascular stroke patients. Stroke lesions may disturp central autonomic network structures and pathways that contribute to erection and physical impairment such as motor weakness,spasticity, bladder, or bowel dysfunction may constitute physical handicaps of sexual activity (Pistoia et al.,2006 and McMahon, 2014). The aim of this study was to detect: The prevalence of erectile dysfunction among male patients with strokeusing the internationalindex of erectile function (IIEF-5). Total testosterone level among stroke male patients Serum prolactin level among stroke male patients. Correlation between site of brain lesion and IIEF-5. Correlation between IIEF-5,testosterone and prolactin level in stroke patient. This study was carried out in Assiut University Hospital (Department of Dermatology,Venereology&Andrology and Department of Neurology) on (80) male patients with ischemic cerebrovascular stroke during the period from April 2016 to May 2017. The patients were subdivided into seven subgroups according to affected brain site as follow: group (A): included (17) patients with middle cerebral artery affection (MCA). The mean age of those patients is (55.71±3.37) years andthe mean duration of stroke is (18.24±7.27) months. group (B): included (13) patients with posterior cerebral artery affection (PCA). The mean age of those patients is (56.23±3.77) years andthe mean duration ofstroke is (13.59±5.88) months. group (C): included (12) patients with anterior cerebral artery affection (ACA). The mean age of those patients is (55.58±3.58) years andthe mean duration ofStrokeis (11.06±5.71) months. group (D): included (11) patients with brain stem affection. The mean age of those patients is (54.00±2.72) years andthe mean duration of stroke is (12.58±4.73) months. group (E): included (10) patients with cerebellum affection. The mean age of those patients is (52.90±2.47) yearsandthe mean duration ofstroke is (10.44±3.42) months.
group (F): included (9) patients with basal ganglion affection. The mean age of those patients is (53.44±3.91) years andthe mean duration of stroke is (9.81±4.56) months. group (G): included (8) patients with multiple areas affection. The mean age of those patients is (60.00±2.07) years andthe mean duration of stroke is (16.55±6.80) months. Each patient was subjected to the following:< A) Medical histor B) Clinical examination C) MRI or CTto diagnose and classify cerebrovascular stroke. D) Evaluation of the erectile function using IIEF-5 E) Measurement of serum prolactin. F) Measurement of serum total testosterone level. The scores of the IIEF-5 showed that(33.8%) of the patients had no erectile dysfunction and (66.3%) had erectile dysfunction with varying severity (22.5% mild, 6.3% mild to moderate, 7.5% moderate and 30.0% severe). There isa statisticallysignificantpositive correlation between IIEF-5 score in each Stroke group. The IIEF-5 score showed significant negative correlation with the age of patients.This means that the ED prevalence increased with the advance of age.The IIEF-5 score also showed significant positive correlation withtestosterone level in stroke patients.The IIEF-5 score showed significant negative correlation with prolactin level Mean testosterone level of stroke patients was (3.64 ± 3.72) ng/ml and mean prolactin level was(23.30 ± 14.00) ng/ml. Statistical analysis showed correlation between agewithserum testosterone and prolactin. There were statistically significant negative correlation between age and serum testosterone and statisticallysignificant positivecorrelation between ageandserum prolactin. The present study showed a high prevalence of erectile dysfunction, low serum testosterone levels and high serum prolactin level in stroke male patients. It’s recommended to do Further studies on a large scale to assess the exact mechanism and management of erectile dysfunction in strokepatients.