الفهرس 
Review of LiteratureOnly 14 pages are availabe for public view
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Abstract
During the past several years, 2D STE imaging had been emerged as a quantitative technique to accurately estimate myocardial function and contractility. 2D STE analyzes motion by tracking speckles in the ultrasonic image is simple to perform, and further processing and interpretation can be done offline after image data acquisition (Zuo et al., 2018). The aim of the present study was to evaluate the diagnostic value of speckle- tracking echocardiography at rest and during dobutamine stress echocardiography in predicting the presence and severity of CAD in patients with chronic stable angina . A total of 144 patients with chronic stable angina scheduled for DSE for investigation of suspected CAD. 44 patients were excluded (37 patients developed chest pain but without RWMA from baseline to peak stress, in two or more contiguous segments. While, 7 patients could not complete the test). Eventually only 100 patients were included in this study. They were subjected to: full history taking, full clinical examination, 12 leads surface ECG, full echocardiography study, high dose DSE, 2D STE to detect GLPSS at rest and stress and then they underwent CA with calculation of SYNTAX score. In the present study, STE at stress showed better agreement with CA than DSE in detecting coronary artery affection, so adding STE results to DSE provided more additional data. This revealed that STE at stress was an excellent predictor for coronary artery stenosis with a sensitivity of (95%), specificity of (90%), PPV of (97.4%) and NPV of (81.8%). So, assessment of GLPSS at peak DSE offered enhanced sensitivity than DSE. This enhanced sensitivity could be valuable in clinical practice when assessing intermediate to high risk patients, in order to minimize false negative rates, which could have a negative impact on their outcomes