الفهرس 
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Abstract
Twenty Five patients received fixed-dose combinations of Tamsulosin 0.4mg/day and Tadalafil 5mg /day for 45 days (groupA) and Twenty Five patients received Tadalafil 5mg /day for 45 days (group B).
The study showed that the fixed-dose combinations of Tamsulosin and Tadalafil significantly improve IPSS score and Qmax more than with Tadalafil 5 mg/day alone. Furthermore, PVRU significantly decreased with the fixed-dose combinations of Tamsulosin and Tadalafil more than with Tadalafil alone. Fixed-dose combinations of Tamsulosin 0.4 mg plus Tadalafil 5 mg were determined to be safe, efficacious, and well tolerated in the subjects investigated, which suggests the new fixed-dose combinations therapy can offer clinically relevant benefits for patients with LUTS complaints and desiring amelioration for comorbid ED complaints.