الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 115 |  |  |
| | | from | 115 | | |
Abstract
Objective: The management of patients receiving oral anticoagulant therapy (OAT) undergoing minor oral surgeries are difficult as these patients presents a significant risk for postoperative hemorrhagic complications, without interruption or diminution of the medication. Aim: This study was performed to evaluate the hemostatic effect of Ankaferd Blood Stopper (ABS) after dental extraction in patients on oral anticoagulant therapy. Materials and Methods: Forty seven patients receiving (OAT), and requiring dental extraction of 60 teeth indicated to extraction were included in this study. All patients were maintained on their (OTA) without modifying the dose. After a traumatic extraction, they were classified into three groups: group 1: Ankaferd Blood Stopper solution was applied in twenty extraction sockets ( 17 patients). group 2: Gelfoam was applied in twenty extraction sockets (15 patients). group 3: Tranexamic acid was applied in twenty extraction sockets (15 patients). Results: As regard Postoperative bleeding,a significant difference between group 1,2 and 3 were found after 5 minutes (p=0.02), 15 minutes and 30 minutes (p<0.001). By company each two groups, there was no significant difference between group1 and group 2 after 5 minutes, 15 minutes and 30 minutes (p1=0.5, 0.7, 1.0 respectively). Furthermore, a high significant difference was recorded between group1 and group 3 after 5 minutes, 15 minutes and 30 minutes (p2=0.009, 0.001, <0.001 respectively). However, there was no significant difference between group 2 and group 3 after 5 minutes (p3=0.056), and high statistically significant difference between groups after 15 minutes and 30 minutes (p3=0.004, p3<0.001 respectively).At one day, there was no significant difference between all groups (p=0.17). Bleeding assessment after 5 days showed grade 0 bleeding in all patients. As regardhealing, no patient had wound infection and the healing process appeared to be normal (p=0.5). Conclusion: ABS is an effective hemostatic agent to control post-extraction bleeding in (OAT) patients.