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Abstract In conclusion, this study aimed to determine the possible mechanical and clinical effects of the different lateral wedge insoles to assess its role in management of the medial compartment knee OA. Both the insoles used suggested clinical symptomatic improvement, while STSLWI suggested more alignment biomechanical improvement that was not proved statistically in the study but was noted for better compliance by patients than LWI in this study. So, STSLWI may provide mechanical benefit for moderate medial compartment knee OA patients. Early diagnosis of OA and management with conventional treatments may prevent progression of the disease, that eventually lead to malfunction and deformities. The forty-eight primary medial compartment knee OA were divided into three groups each of sixteen knees: group A: received conventional physiotherapy for knee OA. group B: received conventional physiotherapy for knee OA and lateral wedge insole (LWI). group C: received conventional physiotherapy for knee OA and subtalar strapped lateral wedge insole (STSLWI). All the three groups received three sessions per week for four months. Summary and Conclusions (145) Exclusion criteria as following: 1. Use of a gait aid. 2. Use of insoles or foot orthotics 3. Lateral tibiofemoral compartment narrowing greater than medial. 4. Foot, ankle, knee, hip, back problems. 5. Hip or knee joint replacement. 6. X-ray [kellgren &Lawrence (K/L) grade 1 or 4]. 7. Valgus knee alignment >185° on a standardized standing knee X-ray. 8. ody mass index ( MI) ≥ 36kg/m². 9. Balance impairment. 10. Other causes of arthritis or musculoskeletal disorder of the lower limb. 11. Mechanical knee trauma, Hypermobility, muscle power less than 3. There is an ongoing need for trials of nonpharmacologic therapies in OA, the use of orthosis in knee OA has positive outcomes. The WOMAC score subscale of pain, stiffness and function showed improvement for all three groups with high significant difference (P˂0.001); While the total WOMAC score showed no statistically significant difference for the patients receiving only physiotherapy group A. Summary and Conclusions (146) As regards FTA, there was a highly statistically significant difference between before and after the study with (P˂0.001) in both wedged insole group B and group C. This suggested that both lateral wedged insoles improved alignment of lower limb. The peak planter pressure in this study showed highly statistically significant difference (P˂0.001) of all areas of both groups with wedge insole before and after the study. While, the group that received physiotherapy only showed in one area MF only. These positive outcomes suggest that the LWI and STSLWI insert may be a viable alternative in the conservative management of patients with medial compartment knee OA. As the insoles improved pain, stiffness, function and total WOMAC score after wearing the insole 4 months with physiotherapy and follow up. The LWI could redistribute the knee internal loading by significantly relieving the contact force and stress on medial compartment of the knee, the use of LWI and STSLWI may prevent the progression of medial knee OA if used in early grades of medial compartment knee OA as grade 2 and 3. Both the insoles improved the lower limb alignment and measurement of peak planter pressure areas that generally improving pain and preventing deformities. Significant differences in pressure distribution mean that Summary and Conclusions (147) the OA groups experienced more impact from the ground during walking. Wearing STSLWI inserted in a flat footwear with no heels was more effective and showed more compliance by patients. Overall, the results of this study were not only suggesting clinically meaningful symptomatic improvement with an inexpensive conservative therapy, but also demonstrate that a less complicated comfortable orthosis of benefit to medial compartment knee OA. This study establishes that plantar pressure measurements as COP can be used to indirectly assess the response in load distribution across the knee joint with medial OA |