الفهرس 
Risk Factors and Pathophysiology of Subarachnoid HemorrhageOnly 14 pages are availabe for public view
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Abstract
Subarachnoid haemorrhage is bleeding into subaracnoid space. It occurs in about one per 10,000 people per year. cerebral vasospasm is acommon complication occurs moslty in about 70 % of patients after spontanous subarachnoid haemorrhage. Refractory vasospam after spontanous subarachnoid haemorrhage can cause a large number of morbidity and mortality in such category of patients .Nimodipne is a calcium channel blocker, when used contiuously into the vasospastic artery of patients complaining of refractory vasospam could be used as a treatment modality to improve the morbidity and mortality in such patients .Aim of the meta-analysis:
To evaluate the effect of continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after spontanous subarachnoid haemorrhage on mortality and morbidity (symptomatic cerebral ischemia).
Studies and participants:
Eight studies were included in the current meta-analysis. These studies are interventional clinical trials in critically ill patients that have aneurysmal SAH complicated by severe symptomatic vasospasm (causing delayed cerebral ischemia and neurological deficit ) which was refractory to standard hyperdynamic therapy (triple –H therapy) and oral calcium channel blockers .
The data that were analysed in this meta-analysis yielded that the total number of the patients that received the treatment was 151(n =151) of this number 82 were females and 69 were males with average age of 50 + 4. Three outcomes were extracted from these 8 studies were as the following :
1-The cerebral angigraphic dilatation with a proportion of 85%.
2-The clinical improvement with aproportion of 57%.
3- The mortality decrease with aproportion of 60%.