الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Background: Spontaneous bacterial peritonitis (SBP) is a potentially fatal condition, characterized by infection of ascitic fluid in absence of any intra-abdominal surgically treatable source of infection. It is the most common infectious complication of cirrhotic patients. SBP is a condition that requires a high index of suspicion, rapid and accurate diagnosis in addition to prompt and effective therapy. It is also characterized by a high recurrence rate within one year of the 1st episode.
Objective: The goal of the present study was to assess the role of ascitic fluid calprotectin in diagnosis of SBP.
Patients and Methods: For this purpose, 60 patients with decompensated liver disease were selected. These patients divided into: Non SBP Group: include 30 patients with cirrhotic ascites without clinical or laboratory evidence of spontaneous bacterial peritonitis. SBP Group: include 30 patients with cirrhotic ascites and spontaneous bacterial peritonitis.
Results: There was highly statistically significance increase in number of cases presented with fever,abdominal pain,abdominal tenderness and upper GIT bleeding in SBP group compared to non SBP group. Splenomegaly and ascitic fluid turbidity were obviously appeared in ultrasound examination of SBP group.
Conclusion: ascitic fluid calprotectin was significantly elevated in SBP patients in comparison with non-SBP patients. In addition, they also correlate well with the PMNLs count and protein levels in ascitic fluid and reliably diagnose SBP.