الفهرس 
Introduction and rationale.Only 14 pages are availabe for public view
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Abstract
Depression is more prevalent among chronic hepatitis C patients. The studies carried out to determine prevalence of depression among hepatitis C patients on recent interferon-free Sofosbuvir (Sovaldi)-based antiviral treatment were scarce, so the present study was carried out to estimate the prevalence of depression among adults with chronic hepatitis C on antiviral treatment in Port Said governorate.
A cross sectional study was carried out at two centers for hepatitis C virus treatment in Port Said governorate; one center is located in fever hospital for non-insured persons and the other is located in Eltadamon (health insurance) hospital for insured persons.
The current study recruited 288 adult (aged18-60) patients from January to August 2017, who had documented chronic hepatitis C infection and were enrolled in the treatment protocol according to supreme council and NCCVH, hepatitis C updated treatment protocol.
The questionnaire was consisted of personal history, socio-economic status scale (SES), medical history and Beck Depression Inventory scale (cut point for depression was > 9).
In current study, females were 52.8% and males were 47.2%. Their mean age was 52.4±7.6. Of all patients 77.1% were married, 50.7 were illiterate, 43.1% were not working, 31.3% has a middle socio-economic level, the great majority of sample (88.2%) was living in urban areas and 25.7% were smokers.
The prevalence of depression was 29.2 % in the study sample. The binary logistic regression revealed that very low, low, middle SES, female gender, young age and illness duration were predictors of depression among the study sample. Antiviral treatment regimens and doses were not associated risk factors for depression among the study sample.