الفهرس 
HysteroscopyOnly 14 pages are availabe for public view
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Abstract
Background: Hysteroscopy is one of the diagnostic methods in gynecology with a relatively recent development. In this method, the whole uterine cavity is directly observed through hysteroscope. In the case of any pathologic lesion, biopsy is taken and treatment is carried out through hysteroscopy if needed. Hysteroscopy has been found to be a totally reliable method for the study of postmenopausal bleeding.
Cervical ripening is a complicated process, being mediated by cytokines, growth factors, hormones and other biochemical compounds.
Misoprostol was first used for prevention of peptic ulcer from the use of non-steroidal anti-inflammatory drugs.
Objects: This study aims to assess the efficacy of dinoprostone compared to misoprostol in cervical ripening in nulliparous women undergoing diagnostic hysteroscopy.
Methodology: a randomized controlled clinical trial comparing dinoprostone versus misoprostol for cervical ripening before diagnostic hysteroscopy in nulliparous women, it included 2 groups, 33 patients each. In the first group named (group D) dinoprostone 3mg was applied vaginally 6 hours before diagnostic hysteroscopic procedure while in the second group named (group M) 400 mcg misoprostol was applied vaginally at the same timing.
Results: There was no statistically significant difference between the groups that received misoprostol or dinoprostone with regard to age, duration of marriage, medical disorder, history of gynecological operations and type of gynecological operations. There was no significant difference between misoprostol and dinoprostone but the use of misoprostol caused slightly less pain compared to dinoprostone. There was no significant difference between misoprostol and dinoprostone but more side effects occurred with the use of misoprostol.
Conclusion: There was no significant difference between dinoprostone and misoprostol in priming of cervix before diagnostic hysteroscopy in nulliparous women regarding ease of hysteroscope entry, pain or side effects.