الفهرس | Only 14 pages are availabe for public view |
Abstract Deltamethrin is a broad-spectrum synthetic type II pyrethroid currently used on crops and in public health application for malaria control. Hepatotoxicity, nephrotoxicity and neurotoxicity are a common side effects of DLM that is widely used as insecticide all over the world. The main pathogenic mechanism following exposure to DLM appears to involve the generation of reactive oxygen species. There are many reports recommending that using of various antioxidants might be effective in alleviating DLM induced toxicities in different tissues. Chlorella vulgaris contains very potent naturally occurring antioxidant and free radical scavenging agents. One of the most important properties of C. vulgaris is its antioxidant activity. Very high amounts of beta-carotene, tocopherol and combined form of these antioxidants make Chlorella a very good source of natural antioxidant along with high protein. These antioxidants can protect the body from oxidative stress. Therefore, the current study was delineated to evaluate the possible hepatorenal and neuroprotective effect of C. vulgaris powder in deltamethrin intoxicated rats. For this purpose, thirty two adult male albino rats were randomly allocated into four equal groups as follow: group I, Control group, received 0.5ml distilled water orally once daily for 8 weeks. group II, Chlorella treated group (CV), received C. vulgaris powder (35mg/ kg b.wt.) orally once daily for 8 weeks. |