الفهرس 
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Abstract
Congenital heart disease (CHD) has become increasingly important in recent years because it is one of the important causes of morbidity and mortality in infancy.The incidence of congenital heart disease (CHD) depends upon various factors—the nature of the sample (all live births or all births), the source of information (birth or death certificates) or on the spot examination by a pediatric cardiologist.The incidence is higher if early spontaneous abortions are also included. Recent studies have reported incidence of CHD to range Between 4.05 to 10.2/1000 births. Earlier reported incidence of CHD of 3-5/1000 live births was low because of inadequate diagnostic techniques and availability of ineffective surgical therapy. The aim of this work is to evaluate the safety and the effectiveness of transcatheter closure of ventricular septal defects as an alternative to surgical approach in children. This current prospective study was conducted on 27 child of both sexes, who are known to have ventricular septal defects; between April 2013 and April 2015. Lock et. al. technique for transcatheter closure of ventricular septal defects was used and during the procedure Transesophageal echo and plan dye screening were done. This study conducted on 27 cases, 12 males (44.4%) and 15 females (55.6%). Their mean age (in years) ± SD equals 8.6 ± 3.4 years (Median age = 9 years).Devices used were of two types; Amplatzer in 13 cases (48.1%) and nit-occluder in 14 cases (51.9%). Pediatric cardiac interventions have established their reliability and scope in the management of congenital heart disease. Success is dependent on selecting the proper procedure for each condition, which may also vary with each patient. Thus, it is highly dependent on the experience and expertise of the operator. With the current rate of technological innovation, more and more surgical procedures will eventually be replaced by catheter-based interventions with a great degree of safety and efficacy. Conclusion: Percutaneous closure of VSDs is possible, safe and effective procedure in highly specialized centers. Appropriate patient selection is of paramount importance to the success of the procedure. Only in very experienced hands can these techniques be carried out safely and complications managed in the proper way. Furthermore, highly specialized surgical backup must always be available.