الفهرس | Only 14 pages are availabe for public view |
Abstract Surgical site infection (SSI) is a leading cause of healthcare-associated infections; it is associated with high mortality, prolonged duration of hospital stay and high use of additional resources.The aggressive use of antimicrobials has significantly improved survival, but has also led to an increased colonization and infection by pathogens that have resistance to current therapies. This study was performed at Menoufia University Hospitals to determine bacterial pathogens frequently causing surgical site infections in our hospitals and their antimicrobial susceptibility patterns. Also, to determine the prevalence of multi-drug resistance among the isolated pathogens, to evaluate the different risk factors for the development of surgical site infection and to assess infection control practice in Surgical Department. This study included 148 patients who were chosen randomly from those who were admitted to General Surgery and Orthopedic Departments of Menoufia University hospitals. The patient personal history was taken including age and sex of the patients, residence, occupation, socioeconomic status, diabetes, obesity, type of surgery (emergent or elective), type of wound (clean, clean contaminated, contaminated or dirty), use of antimicrobial prophylaxis, length of the procedure, foreign material in the surgical site e.g. drainage and length of postoperative stay. The specimens collected were wound swabs taken by dry sterile cotton tipped swabs or aspirated pus by sterile disposable syringes from the surgical wounds. The specimens were processed according to standard microbiological methods. Antimicrobial susceptibility was determined by disk diffusion method and results were interpreted according to the Clinical and Laboratory Standard Institute (CLSI) guidelines. |