الفهرس 
Anatomty Of The LiverOnly 14 pages are availabe for public view
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Abstract
Focal lesions of the liver can be benign or malignant. Therapy an accurate diagnosis is required,which in turn relies primarily on accurate imaging diagnosis and image-guided biopsy. MRI, as opposed to CT, can provide further information useful in the diagnosis of HCC, also in the examination without injection of contrast medium.MRI having many sequences, markedly helps in the detection of small lesions and in reaching the diagnosis easily even without contrast injection or the need for biopsy . One of the sequences that can provide information is the diffusion sequence (DWI).
In current clinical practice the main strengths of DWI are to increase the confidence in diagnosis of HCC especially when intravenous contrast
administration is not possible or for small lesions adjacent to vessels. This is very helpful in the setting when post-contrast images cannot be obtained due to poor GFR or history of allergic reaction to contrast.
Both qualitative evaluation of high b-value DW-MR images and quantitative evaluation of ADC maps are employed for lesion characterization. The ADC values of benign lesions are significantly higher than those of malignant lesions, with variable degrees of overlap between the pathological entities.
This study proves that ADC is a very useful test to differentiate focal liver lesions in conjunction with the other anatomical imaging sequences.
The major limits of DWI are inconsistency in image quality, which is heavily effected by magnetic field inhomogeneity artifacts, and limited models to correlate quantitative measurements to histopathology: an important technical development could be focused on the amelioration of the image quality with a specific software able to reduce the artifacts, moreover, the radiologists would need of more reliable prognostic models to more frequently use this technique.