الفهرس 
Acute Myocardial InfarctionOnly 14 pages are availabe for public view
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Abstract
Coronary artery disease (CAD) accounts for 70 to 80% of deaths among men and women in peoples older than 65 years of age and is responsible for 50% of patients hospitalized for acute myocardial infarction (MI).(201)
For patients with symptomatic chronic coronary artery disease, revascularization therapy provides symptom relief, and certain high-risk subsets have improved survival.
The ECG remains a simple yet powerful tool in the assessment of reperfusion efficacy and prognosis following ST-segment elevation myocardial infarction (STEMI).
Less attention has been given towards the evolution of concomitant ST-segment depression in patients with STEMI. The mechanism of concomitant ST-segment depression in patients presenting with STEMI continues to be the subject of debate.
This study aimed to evaluate the effect of reciprocal ST depression resolution between patients with ST-segment elevation myocardial infarction (STEMI) treated with IV thrombolytic therapy.
This study was carried out on 100 patients with acute ST elevation myocardial infarction with reciprocal ST segment depression who were amenable to thrombolytic therapy within first 6 hours of presentation were admitted to our hospital. Informed consent was taken, then serial ECG, serial cardiac biomarker, routine lab including renal function, echocardiography and diagnostic coronary angiography was done to all patients.
Serial ECGs were taken at baseline and at 90 minutes after thrombolytic therapy then analyzed for STDR.
Patient were divided into 2 subgroups (1) with STDR (> 50%) and (2) with no STDR(<50%) then both subgroups were observed and compared for demographic data, risk factors, physical examination, CA finding, MACE in hospital and MACE in one month.
There was better outcome in patients who had STDR in comparison to other patient regarding Killip class on presentation showing better Killip class (p- value0.001),
Moreover, regarding coronary angiography patients who had STDR found to have more TIMI 3 flow in the culprit artery than other patients (p- value0.020). And patients who had no STRD had more number of vessels affected (p- value0.001).
Keywords: Reciprocal ST-segment Depression; Thrombolytic Therapy