الفهرس 
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Abstract
The liver represents the largest organ in the body. It is the main site of most metabolic
reactions it has a pivotal role in regulation of physiological processes. It is involved in several
vital functions such as metabolism, secretion and storage. Furthermore, detoxification of a
variety of drugs occurs in liver. Liver disease remain one of the seriouse health problems and
constitute a global concern. Despite advance in modern medicine, there is no effective drug
available that stimulates liver function, offer protection to the liver from damage or help to
regenerate hepatic cells. Therefore it is necessary to search for some herbs for the treatment
of liver diseases to replace currently used drugs. This study was carried out to study the effect
of some herbs of thyme, and chicory powder leaveson hepatoprotective changes of male
albino rats. Thirty two adult male white albino rats, weighting (186±8g) were used in this
experiment. All rats were fed on basal diet for week. After this adaptation period, rats are
divided into 8 groups group (1) rats will feed on basal diet as a control negative. all rats
were injected subcutaneously at a dose of 0.2ml/100gbody weight of 40ml/l ccl4 dissolved in
paraffin oil. carbon tetrachloride was injected two times per week for 2 consecutive weeks.
group (2) appositive control group. and rats fed on basal diet and 1.5-3% thyme ,chicory,
and mixed of it. The experimental will take 28 days, at the end of the experimental period
each rat weight separately then, rats are slaughtered and collect blood samples. Blood
samples were centrifuged to separate blood serum, then kept in deep freezer till using.
extracting the liver, the following test was conducted for pathohistological examination
The obtained results could be summarized in the following:
The highest body weight gain recorded for group rats fed on 1.5 % chicory
(15.15±1.4 g) . The highest food intake recorded for group rats fed on 1.5 % thyme. The
lowest serum AST level recorded for 3 % mixed thyme and chicory, while, the highest value
recorded for 3 % chicory with significant difference. The lowest serum cholesterol level
recorded for 3 % mixed thyme and chicory, the mean value was 153.48±3.76 mg/dl while, the
highest value recorded for 3 % chicory with significant difference. The total protein levels of
control negative recorded the higher value compared with control positive with significant.
The highest serum albumin level recorded for 3 % mixed thyme and chicory and 3% chicory
with no significant difference (P<0. 01), the mean value was 3.64±.81 and 3.62±.82 mg/dl,
respectively. While, the lowest value recorded for 1.5 % chicory and 1.5 % thyme leaves with
no significant difference (P<0. 01), which recorded 3.23±.80 and 3.24±.8 mg/dl, respectively.
the highest catalase level recorded for 3 % mixed thyme and chicory and 3% chicory with no
significant difference (P<0. 01), the mean value were 1.27 and 1.22 mg/dl, respectively.
While, the lowest value recorded for 1.5 % chicory and 1.5 % thyme with no significant
difference (P<0. 01), which recorded 1.11 and 1.17 mg/dl, respectively. The highest
glutathione level recorded for 3 % mixed thyme and chicory, the mean value was 48.99 mg/dl.