الفهرس 
Physiology of the Thyroid GlandOnly 14 pages are availabe for public view
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Abstract
Introduction: The strong relationship between thyroid hormones and the coagulation system has been appreciated since the beginning of the past century. Various coagulation abnormalities have been seen during the course of thyroid disorders and hyperthyroidism was found to be associated with potential procoagulant changes in the hemostatic system. Although hyperthyroid patients are prone to develop thromboembolism, bleeding due to various coagulation defects was, also, reported.
Aim of the Work: The purpose of the present study is to investigate the changes in the hemostatic system mediated by hyperthyroidism in an experimental rat model with special emphasis on the possible role of oxidative stress in this aspect. Also, the study will explore whether green tea or exercise training will have any beneficial effect on these hemostatic changes which will help to consider them as adjuvant therapy in the hyperthyroid state.
Materials and Methods: This study was carried on (46) adult Wistar male rats weighing 260-330 grams purchased from the experimental animal farm in ElGiza. Rats were maintained in the animal house of Physiology Department, Faculty of Medicine, Ain Shams University under standard conditions of boarding with access to food and tap water ad libitum. The diet consisted of bread, milk and green vegetables. Rats were exposed to the new environment for 7 days prior to experimental protocol to decrease the possible discomfort of animals.
Results: The results encountered in the present study, reflecting the effects of hyperthyroidism and of green tea supplementation and exercise training in rats subjected to hyperthyroidism are displayed in tables
Conclusion: The purpose of the present work was to determine alterations in the hemostatic mechanism in an experimental model of hyperthyroidism. Also, to throw light on the possible beneficial effects of green tea supplementation and exercise training in alleviating the hyperthyroidism-mediated hemostatic derangements in a trial to introduce useful adjuvant non drug tools in hyperthyroid conditions