الفهرس 
Introduction & Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
This study was carried out at Obstetrics and Gynecology Department of Shebien Elkom Teaching hospital from June 2015 to January 2016 on 110 pregnant women (58 cases were gestational hypertension , 44 cases were mild preeclampsia and 8 cases were chronic hypertension) who attended the obstetric out-patient clinic for routine antenatal care examination at 30-40 weeks .
In our study we aimed to evaluate the effect of ”methyldopa” on uteroplacental and fetal hemodynamics in hypertensive disorders of pregnancy.
The study group was subdivided into 3 groups:
a) Pregnant women with mild preeclampsia.
b) Pregnant women with gestational hypertension.
c) Pregnant women with chronic hypertension.
The study participants haven’t received antihypertensive medication before interviewing them at the antenatal clinic. Alpha methyldopa (Aldomet® 250 mg tab) (Kahira/ MSD) was given to them in different doses (750 mg – 2250 mg) in order to control their blood pressure. Doppler ultrasound was done before administered antihypertensive medication and after adequate control of blood pressure via either using alpha methyldopa alone or being combined with nifedipine (Epilat 10 mg cap) (EIPICO), if needed, when using alpha methyldopa alone failed to control blood pressure.
Our study had shown that antihypertensive medication (Alpha methyldopa) didn’t affect fetal hemodynamics circulation in term of Doppler indices of umbilical artery and middle cerebral artery (PI, RI & S/D ratios), although there was significant effect on maternal Doppler variables, as there was highly significant effect on Doppler indices of uterine artery (PI, RI & S/D ratios)