الفهرس 
Physiology of the CoagulationOnly 14 pages are availabe for public view
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Abstract
Background: Venous thromboembolism (VTE) is a disease that includes both deep vein thrombosis (DVT) and pulmonary embolism (PE). It is a common lethal disorder that affects hospitalized and nonhospitalized patients, is often overlooked, and results in long-term complications including chronic thromboembolic pulmonary hypertension (CTPH) and the post-thrombotic syndrome (PTS).
Aims: The aim of this work is to discuss different types of anticoagulants with different duration for treatment of venous thromboembolic patients.
Methodology: Blood coagulation forms part of a series of haemostatic reactions, including plasma, platelets, and vascular components. Platelets adhere to the damaged endothelium or to the subendothelium under the effect of adhesive proteins, and after being activated they aggregate and expose binding sites for the coagulation factors. Therefore, platelets help to concentrate and potentiate the coagulation reactions on damaged blood vessels.
Conclusion: The main goals of treatment for DVT include prevention of PE, the PTS, and recurrent thrombosis. Once VTE is suspected, anticoagulation should be started immediately unless there is a contraindication. Different types of anticoagulant can be used including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), or fondaparinux followed by an oral anticoagulant (vitamin K antagonist [VKA]), Direct thrombin inhibitors.