الفهرس 
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Abstract
Helicobacter pylori infection has a wide spread distribution, but
the prevalence varies between developed and developing countries
Infection is usually acquired during childhood.
To define the epidemiological character of a disease, one needs
a diagnostic test that is inexpensive, reliable and readily available
across a broad spectrum of population. The development of new noninvasive
reliable serological tests has opened the door for
epidemiological exploration.
The objective of this study was to determine the seroprevalence
of H. pylori infection among apparently healthy Egyptian children
living in qulubia governorate and belonging to various social classes,
also to assess the risk factors influencing the prevalence of
Helicobacter Pylori infection, and to study the effect of H. pylori on
growth of the studied cases.
A Series of four hundered (400) apparently healthy children
Attending basic schools were included in our study, were assayed
for the presence of Anti- Helicobacter pylori antibody (IgG)
measured by enzyme linked immunsorbant microassayed test
(ELISA) and studied for the effect of age, sex socioeconomic
background and other risk factors who influencing the prevalence of
H. pylori infection.
Their ages ranging from 6years to 13 years. Serum Samples
were withdrawn from the above cases and assayed for the presence of
Anti- Helicobacter pylori antibody.
It was observed that the overall H. Pylori seroprevalence in
cases of the study were 44% (176/400) and frequency of seropositive
cases increased highly significantly with advances of age.
In trial to study risk factors for acquisition of H. Pylori
infection in our cases group, we found a highly significant difference
between seropositive and seronegative cases regarding
(Socioeconomic status, breastfeeding cases, duration of breastfeeding,
educational status of parents, Family history of gastric troubles and
cases who had not owned domestic animals).
On the other hand, we found no significant differences between
seropositive and seronegative cases regarding (Sex, water supply,
different blood groups)
Regarding occupatinal status of parents, we found that H. pylori
prevalence was highly significant higher among cases of farmers than
among cases of blue collar and white collar workers; moreover cases
living in white collar families had a lower risk of being positive for H.
pylori infection.
Studying dietary factors, we found that high salty foods
intake were highly statistically significant risk factor, also there was
significant difference regarding high fruits, Vegetables and high milk
intake while there was no significant difference regarding (, fish,
chicken, been, rice and cheese) intake.
In trial to study effect of H. pylori on growth, we found only a
significant difference in height between infected and non-infected
children in those cases older than 6 years to 9years compared to the
other age groups where no significant difference in stature was found
between infected and non-infected cases. Moreover, significant
difference in the centile value for weight was detected between
infected and non-infected cases among the two age groups.