الفهرس 
Normal Sleep & Sleep DisordersOnly 14 pages are availabe for public view
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Abstract
Prof. Dr. Eman Mahmoud Fouda ,Prof. Dr. Hanan Mohamed Ibrahim, Prof. Dr. Hala Hamedy Shaban, Dr. Mahitab Morsy Hussein, Amira Shepl Hamed Saleh
Faculty of Medicine – Ain Shams University
Introduction: Sleep apnea and other sleep-related breathing disorders constitute the greatest number of sleep disorders seen by sleep medicine, pulmonary, and general practitioners in the outpatient setting. SBD has been associated with considerable morbidity. Lack of knowledge regarding the diagnosis and consequences of pediatric SBD has come to the forefront of child health in the past decade, highlighting the growing need for further scientific advances in the field. Materials and Methods: This case-control study was carried out in Pediatric chest clinic, Children Hospital, Ain Shams University during the period of June 2015 to January 2016.The study included 50 children, who were further subdivided into 20 asthmatic children and 20 chronic lung disease (CLD) children from those regularly attending the Pediatric chest clinic for follow up. 10 apparently healthy children were chosen as control group, who were recruited from the outpatient clinic of Children Hospital, Ain Shams University. Results: Positive Pediatric sleep questionnaire scores was recorded in 60% of asthmatics, 44% of CLD patients and 30% of control group, however, Polysomnogram confirmed sleep breathing disorder diagnosis in 35% of asthmatic, 20% in CLD patients and 10% in control group.A statistically significant increase in N.of arousals, sleep latency and O2 desaturation index in asthmatic patients compared to control.(P˂0.005).A statistically significant decrease in sleep efficiency and Spo2%in asthmatic patients and patients with CLD compared to control group. (P˂0.005).A statistically significant increase of apnea –hypopnea index (AHI) in the studied patients compared to control group.
Patients with sleep breathing disorders showed a statistically significant decrease in FEV1(% pred) and FVC(% pred) compared to those patients who did not have sleep breathing disorders. A statistically significant correlation between duration of illness and AHI˃ 5 was detected.A statistically significant inverse correlation between FEV1(% pred) ≤ 80 and O2 desaturation index, and statistically significant correlation between FEV1(% pred) ≤ 80 and Spo2 %, among patients who had SBD diagnosis by polysomnogram. Allergic rhinitis, second hand smoker, low socio-economic class and FEV1(% pred) ≤ 80, were found to be independent predictor factors for sleep breathing disorders.
The Arabic translated Version of the Pediatric sleep in diagnosis of sleep breathing disorder confirmed by polysomnogram shows 100% sensitivity and specificity of 63.16%, with positive prediction by 46.15% and negative prediction of SBD by 100%. Conclusion: Sleep Breathing disorders was recorded in significant percent in children was asthma and it was correlated to the asthma control level, asthma severity and duration of illness. Sleep breathing disorder was recoded in significant percent among children with chronic lung diseases.
Key words: FEV1:Forced expiratory volume in first second ,SBD :Sleep breathing disorders, PSG : Polysomnography.