الفهرس 
The Uterine CervixOnly 14 pages are availabe for public view
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Abstract
The current study was conducted at Ain Shams University Maternity Hospital during the period between January 2012 and July 2013. A total of 130 pregnant women being at a high risk of preterm delivery were included in the study after registering 161 ones with escape of 31 women.
The Primary objective was to compare the efficacy of the CervilenzTM as a cheap and easy method to the transvaginal ultrasound cervical length measurement to detect the short cervix in prediction of spontaneous preterm delivery.
One hundred and thirty women were enrolled according to inclusion and exclusion criteria as outpatients at the antenatal care clinic and emergency room attached to the maternity hospital and also inpatients admitted to the hospital.
After recruitment and written informed consent was signed, each case underwent measurement of the cervical portio length (CPL) using CervilenzTM then each case underwent cervical length measurement through the transvaginal ultrasound by a second expert examiner, then the data collected was analysed according to our enrollement data and the Statistical protocol.
• All enrolled cases shared one or more of the following risk factors of developing preterm birth;
a. Gestational age: 28-34 weeks as calculated according to the last menstrual period (LMP)
b. Having prior preterm birth.
c. Having any cause of uterine over distention (as polyhydraminous, twin or higher-order etc…)
d. Having any uterine abnormalities or malformed uterus (as uterine submucous fibroid, cervical surgery as cone biopsy, septate or bicornuate uterus etc…).
All enrolled cases didn’t have
• Mental condition rendering the patient unable to understand the consequences of the study.
• Cervical cerclage.
• Cases having risk of indicated preterm birth as (preeclamsia, placenta previa, etc…).
METHODS:
• Full history , complete clinical examination ,Gestational age and fetal viability confirmed by ultrasonography were performed.
• Routine antenatal laboratory investigations, including:
(Blood grouping, Rh typing, full blood count and urine analysis ,Transvaginal ultrasounds were done with assessment of Whole cervical length measurement from the internal os till the external one.
CervilenzTM
It is a low-cost screening tool for objectively assessing cervical portio length. It is a disposable measuring probe with a movable flange to measure the distance from the lateral fornix to the distal end of the cervix under direct visualization
Cervical portio length measured by Cervilenz was significantly and persistently shorter than cervical length measured by TVS [mean paired difference (MPD) = 0.35 cm, 95% CI (0.34 to 0.37), p<0.001
There were no significant differences between women who delivered at term and women who delivered preterm regarding age and parity. The BMI was, however, significantly higher in women who delivered preterm
There was a significant positive correlation between cervical length measured by TVS and cervical portio length measured by Cervilenz
A cervical length measured by TVS ≤ 3.32 cm was associated with preterm labor with a sensitivity of 100%, specificity of 87.7%, PPV of 53.3%, NPV of 100%, LR+ of 8.1 and LR- of zero.
A cervical portio length measured by Cervilenz ≤ 3.03 cm was associated with preterm labor with a sensitivity of 100%, specificity of 91.2%, positive predictive value (PPV) of 61.5%, negative predictive value (NPV) of 100%, positive likelihood ratio (LR+) of 11.4 and negative likelihood ratio (LR-) of zero.