Search In this Thesis
   Search In this Thesis  
العنوان
Role of MRI diffusion in evaluation of renal masses /
المؤلف
Tawfeek, Mai Abdel-waheed.
هيئة الاعداد
باحث / مى عبدالواحد توفيق
مشرف / ايناس احمد عزب
مشرف / يسرا عبدالظاهر عبدالله
الموضوع
MRI- evaluation of renal masses-
تاريخ النشر
2014
عدد الصفحات
139 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

from 139

from 139

Abstract

Renal masses are being discovered more frequently in the last years due to advances in cross sectional imaging. US remains the first and initial imaging modality for detection of renal masses and tumors, then CT and MR are used for better detection, characterization and staging of these masses.
Accurate characterization of renal masses is essential to ensure appropriate case management and to assist in staging and prognosis and to differentiate surgical lesions from nonsurgical lesions.
Diffusion-weighted Imaging (DWI) is a new functional imaging technique that derives image contrast from differences in water molecule diffusion within tissues. Cellular tissues as tumors that exhibit the greatest degree of restricted diffusion are seen as areas of retained (bright) signal on high b-value images and show low signal intensity on the corresponding ADC map with low ADC value.
DW MRI does not rely on intravenous contrast, so patients with renal failure who are at risk for nephrogenic systemic fibrosis or nephrotoxicity may particularly benefit from this technique in the evaluation for renal and upper urinary tract cancer in a noninvasive manner.
Because there is wide range and overlap between the ADC values of benign and malignant lesions, the use of ADC value alone may lead to inaccurate assessment of renal lesions. The combination of conventional MRI and ADC value in the diagnosis of renal lesions can increase the diagnostic accuracy.
We recommend that DWI with low and high b value (b 0-800) and quantitative ADC measurements to be added to a routine renal MR imaging protocol as it is rather an accurate method for renal lesion characterization & can be useful in the differentiation of benign and malignant renal lesions.