الفهرس 
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Abstract
The main objective of this study was the following:
1- To determine the main predominant salmonella serotypes in broiler breeder flocks in the last few years (2009-2011) in Egypt and the most sensitive antibiotics.
2- To evaluate the efficacy of the salmonella live vaccines in broiler breeder flocks in Egypt.
During the period 2009-2011 a total number 8232 broiler breeder birds represent 35 broiler breeder flocks lo¬cated in Alexandria, Behera and Giza governorates were examined for the presence of salmonella, include 13 flocks in 2009, 12 flocks in 2010 and 10 flocks in 2011. from 4383 samples collected from 13 broiler breeder flocks in 2009 and examined, 65 samples out of them were salmonella positive (1.48 %), 35 salmonella isolates (53.8 %) were typed and 30 salmonella isolates (46.2 %) were untyped. The most prevalent serotype was S. kentukey (23.1%), S. typhimurium (15.4 %), S. new port (7.7 %), S. derby (3%), S. Saint Paul (3 %) and S. enteritidis (1.5 %). In 2010 a total number of 1811 samples were collected from 12 broiler breeder flocks, 53 samples out of them were positive for salmonella (2.9%), 29 isolates (54.7%) were typed and 24 isolates (45.3 %) were untyped. The The most prevalent serotype S. kentukey (26.4 %), S. rissen (9.4%), S. enteritidis (5.7%), S. magherafelt (5.7%), S. virchow (3.8 %), S. ferruch (1.9 %), and S. heidelberg (1.9 %). In 2011 A total number of 2038 samples were collected from 10 broiler breeder flocks, 13 samples out of them were salmonella positive (0.6 %) 5 isolates from positive samples were typed (38.5 %) and 8 isolates untyped (61.5 %). The most prevalent serotype was S. kentukey (23.1 %), S. haifa (7.7 %) and S. typhimurium (7.7 %). All salmonella isolates were subjected to antibacterial sensitivity test and the results revealed that all Salmonella isolates were sensitive to ciprofloxacin, colistin and norfloxacin and most of isolates were sensitive to neomycin, enrofloxacin, cloramphinicol, and gentamicin. While, all isolates were resistant to amoxicillin, ampicillin, oxanilic acid, streptomycin, lincospectin, spectinomycin, rifampicine, aparamycin, clindamycin.
Experiment:
One broiler breeder flock was vaccinated by two types of live salmonella vaccines against S. enteritidis and S. typhimurium at the same time at the 2nd day, 7th week and 17th week of age in drinking water according to the recommendations of the manufacturer and did not given any antisalmonella treatment in feed or drinking water.
Another broiler breeder flock of the same conditions was left as a control flock not vaccinated but treated for salmonella in feed and drinking water.
Results:
The results of performance of both the vaccinated and control flocks were recorded during rearing period as mortality, Uniformity and feed consumption.
The results during production period including monitoring of salmonella, The comparison between weekly egg production percentages, comparison between cumulative total egg produced per hen, comparison between cumulative H.E. / H.H., comparison between the percentage of H.E. / T.E., comparison of fertility and comparison of hatchability between vaccinated and non-vaccinated flocks were recorded and all results indicated that the performance of vaccinated flock was better than non vaccinated flock.
Also, in the present study the results of performance of 9 broiler flocks produced from vaccinated flock and 9 broiler flocks produced from non vaccinated flock were recorded to compare between them and the results indicated that the performance of broiler flocks produced from vaccinated flock were better.
from these results we concluded that the performance of the vaccinated flock was better than the non vaccinated flock in rearing and production period. Also, the performance of the broiler chicks produced from vaccinated flock was better than those produced from the non vaccinated flock.