الفهرس | Only 14 pages are availabe for public view |
Abstract Periodontal disease is a chronic destructive inflammatory disease affecting the tooth-supporting tissues and is one of the most prevalent chronic infections in humans. The disease is caused by dental plaque, a biofilm in which gram-negative anaerobic microorganisms dominate. Treatment of periodontal diseases principally focus on addressing the etiologic bacteria or biofilm. The bacterial biofilm is disrupted and removed via scaling and root planning (SRP) procedures. Because mechanical means alone have limitations especially in the interproximal areas, greater interest has shown in chemical means. Therefore, chemotherapeutic agents can play a vital role as adjuncts of mechanical plaque control methods. Chlorhexidine is considered the gold standard agent largely used as a mouth-rinse for its clinical efficacy in chemical plaque control. However, it is expensive and has unwanted side effects such as extrinsic tooth staining, unpleasant taste, taste disturbance, sensitivity changes in tongue, and pain. Thus, the treatment with natural products could be used. Among the known natural antibacterial agents is Punica granatum (pomegranate) which also has an anti-inflammatory, antioxidant properties. Therefore, the goal of this study was to investigate the possible antimicrobial efficacy of different concentrations of pomegranate peel extract on bacterial plaque and to compare the clinical and microbiological effects of its use as a mouthrinse versus chlorhexidine mouthrinse as an adjunctive therapy to scaling and root planing in the treatment of chronic gingival and periodontal diseases. |