الفهرس | Only 14 pages are availabe for public view |
Abstract Hospital-acquired infections are an important cause of morbidity and mortality in neonates admitted to NICUs Physiologic immaturity of the adaptive immune response, low GA, low birth weight and invasive procedures are major risk factors for neonatal sepsis. Because the innate immune response represents an important first-line defense mechanism against infections in newborns, it is possible that genetic and/or developmental variations in the innate immune response play a significant role in modulating the predisposition to severe infections. MBL, a member of the collectin family, is produced by the liver as an acute phase protein and its blood levels increase significantly in response to infections. In the present study , Patients were divided into two groups: Infants without sepsis who did not develop clinical and/or laboratory signs of infection during their hospital stay and Infants with sepsis who developed at least one episode of sepsis. |