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العنوان
Non conventional methods for diagnosis of mycobacterium tuberculosis /
المؤلف
Abd El-Aziz, Nedal Mahmoud.
هيئة الاعداد
باحث / نضال محمود عبدالعزيز
مشرف / رمضان عبدالمجيد محفوظ
مشرف / مني بدرالدين الحديدي
باحث / نضال محمود عبدالعزيز
الموضوع
Tuberculosis - Diagnosis.
تاريخ النشر
2012.
عدد الصفحات
133 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأحياء الدقيقة (الطبية)
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Microbiology
الفهرس
Only 14 pages are availabe for public view

from 157

from 157

Abstract

Tuberculosis is considered a significant cause of morbidity and mortality in resource-poor nations. MTB can be diagnosed by many conventional diagnostic methods as staining by Z.N, Kinyoun stains or Auramine-based stains, many culture media can also be used as L.J, Ogawa and Middlebrook and tuberculin skin test. Recently, many non conventional diagnostic tools for detection of MTB as (1) immunological: antigen detection, antibody detection and Interferon Gamma Release Assays (IGRAs) (2) Automated culture methods: BACTEC TB- 460, Mycobacteria growth indicator tube (MGIT), BacT/ Alert 3D. Detection of genomic contents of MTB is done by PCR sequencing, DNA probe. Phenotypic methods by detection of mycolic acid derivatives different chromatography methods. It is essential for detection of antibiotic associated drug resistant mutants and drug susceptibility testing by many diagnostic tools.