الفهرس | Only 14 pages are availabe for public view |
Abstract The transition from the early metabolic abnormalities that precede diabetes, IFG and/or IGT, to diabetes may take many years; however, current estimates indicate that most individuals (perhaps up to 70%) with these pre-diabetic states eventually develop diabetes. The original FPG range (110–125 mg/dl) was changed in 2003 to 100–125 mg/dl, so that the population risk of developing diabetes with IFG would be similar to that with IGT. The change in the cut point increased the overall prevalence of IFG approximately three to four fold. It is clear, however, that IGT and IFG do not define the same individuals. The prevalence of IFG and IGT varies widely, with recent data from the U.S. indicating the prevalence of IFG to be ~26% and somewhat older data showing a 15% prevalence of IGT. Individuals with both IFG and IGT have approximately double the rate of developing diabetes compared with individuals with just one of them. However, with recent changes in the cut point defining IFG, the risk of developing diabetes associated with IFG needs to be reevaluated. |