الفهرس 
Energy and NutritionOnly 14 pages are availabe for public view
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Abstract
Metabolism is acutely modified by any form of severe disease. Resting energy expenditure is also influenced by malnutrition.
Malnutrition may be linked to higher morbidity and mortality rates and increased length of stay. Thus, caloric requirements & specific metabolism are essential components of the care of these patients.
So accurate determination of REE is necessary in ICU patient who are receiving nutritional support to ensure that their needs are met and to avoid complication of under or over feeding.
Vmax Encore Apparatus (indirect calorimetry) is still the gold standard method to obtain accurate, valid and reliable evaluation (measurement) of REE in both normal and overweight critically ill patients and to determine nutritional support in those patients, in comparison of H-B equation.
Despite that, Indirect calorimetry require metabolic, heamodynamic stability to obtain accurate measurement, trained personnel to perform it and time consuming, in addition; it’s expensive specialized equipement that is not universally available.
The H-B equation still has long been widely used method of energy expenditure estimation in hospitalized patients including critically ill patients as this equation is easy to use, does not require trained personnel to perform it , inexpensive and universally available. So it’s considered to form the basis of nutritional support regimen and the routine used method in practise.
The aim of this work was to estimate variables that influence REE of mechanically ventilated patients and to compare REE measured by indirect calorimetry with REE calculated by using Harris-Benedict equations.
The present study was conducted upon 30 intubated and mechanically ventilated patients for >24 hr. Those patients were admitted at Respiratory Intensive Care Unit (RICU) at chest department of Ain Shams University Hospitals in the period from March 2010 to March 2011.
Admission history, clinical examination, laboratory investigations, calculated REE using Harris-Benedict (H-B) equation after correction according to Long et al hypermetabolism factors and measured REE by Vmax Encore apparatus revealed that:
• There was no statistically significant relationship between measured REE and predicted BMR (Basal metabolic rate) by Vmax Encore apparatus; however, the measured REE is still slightly higher than the predicted BMR.
• There was no statistically significant relationship between calculated REE by H-B equation and measured REE by Vmax Encore apparatus. However, the calculated REE by Harris-Benedict equations was (1599.8 ± 406.84) higher than the measured REE (1454.47 ± 423.13) by Vmax Encore app.