الفهرس | Only 14 pages are availabe for public view |
Abstract Portal hypertension is a common and serious problem in children, various portosystemic collateral channels develop as a result of portal hypertension. Oesophageal varices develop as a result of portal hypertension, and bleeding oesophageal varices is a major complication. Endoscopic I. sclerotherpay, and pharmacologic vasoactive drugs are used for proper control of acute bleeding episodes; prevention of early rebleeding, and in eradication of oesophageal varices. The aim of the present study was to evaluate the efficacy of injection sclerotherapy in control ofacute bleeding in comparison with the additional use of octerotide for proper control of acute bleeding and prevention of _......-- early rebleeding, also to evaluate the efficacy of sclerotherpay on variceal eradication and prevention of recurrence. The study comprised 40 children who were divided into 2 groups. All children had oesophageal varices as detected by upper gastrointestinal endoscope. The first group, 20 children subjected to endoscopic sclerotherapy only while second group subjected to combined injection ;. sclerotherapy and octerotide infusion for 3 days after sclerotherpay session in a dose of 1 ug/kg/hour. All cases of the 2 groups were subjected to the following investigations: • Complete blood count. • Liver function test. - ’. • Prothrombin time. Hepatitis markers including hepatitis B surface antigen and hepatitis C antibodies. Liver biopsy for selected cases. Doppler ultrasound. Abdominal ultrasound. |