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Abstract the current Study has been carried Out To Investigate the possible cardiotoxic Effects Of Tricyclic Antidepressants Especially Imipramine Hydrochloride and Dothiepin Hydrochloride In Conclusion,treatment With Triclic Antidepressant toxicity Still Presents One Of The Most Confusing And frustrating Problem For Physicians Dealing with these Cases As The tricyclic Antidepressants Toxicity became One of the Most Striking And Leading cause Of Death In the Poisoning control Centers Not In Egypt Alone but Allover the world. This May Be Due To The Wide Use And Availability Of Such agents |