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Abstract This study was proposed to demonstrate the different uses of AlloDerm in otorhingology: 1- The first aim in the present study was to evaluate the use of AlloDerm in surgical repair of tympanic membrane perforations. 2- The second aim was to evaluate the use of AlloDerm in surgical reconstruction of the saddle-nose deformity. In most individuals with saddle-nose deformities, treatment is aimed at surgical reconstruction of functional and aesthetic deficits. 3- The third aim was to evaluate the use of AlloDerm in surgical repair of nasal septal perforations. Conclusion: Therefore, the use of AlloDerm dermal graft in otolaryngology is promising and advantageous in many aspects: 1- Its ready availability. 2- Ease of handling and application. 3- Predilection for host tissue integration. 4- Lack of immunogenicity. 5- Low risk of disease transmission in contrast to other graft materials. 6- It reduces the operative time and surgical costs. 7- It reduces the extent of surgical dissection. 8- No donor site morbidity. 9- It appears to give a beast results and success rate in comparison with other grafting materials. 10- It is a cellular graft thus removing the problem of antigenic recognition. 11- AlloDerm dermal graft is distinguishable from allograft skin only by its lack of cell components. 12- In addition to its possibility for use in any location on the body, it is easier to keep than typical tissue bank skin, because it can be refrigerated. Tissue bank skin must be kept in freezer on dry ice. The AlloDerm skin is freezer dried so surgeons can rehydrate it just before surgery. 13- Perhaps its most significant advantage lies in its ability to facilitate the application of a well tolerated graft material in an out patient setting. |