الفهرس Only 14 pages are availabe for public view
 |  | from | 165 |  |  |
| | | from | 165 | | |
Abstract
Treatment of chronic periodontitis affected patients is based on measures for reduction/eradication of periodontal pathogens and alteration of the systemic and local host susceptibility. This study aimed to evaluation the effects of topical application of some antimicrobial agents in management of chronic periodontitis.
This study was carried out on 30 patients (aged between 25-55) with moderate to sever chronic periodontitis. All patients demonstrated good general heath, no history of antimicrobial therapy for the last 6 months, and no periodontal treatment prior to initiation of the present study. They were divided into equally two groups. Group I: received CHLO-SITE gel plus scaling and root planning in one side and scaling and root planning alone in other side. Group II: received ATRIDOX gel plus scaling and root planning in one side and scaling and root planning alone in other side,
Each individual was subjected to the following measurements:
• Evaluation of the periodontal condition with criteria of Gingival Index, Plaque Index, Periodontal pocket depth, Clinical attachment, Periodontal Index. using clinical pre and post treatment to detect the outcome of the treatment modality either negative or positive effect.
• Dental plaque samples initially and at 3,6,9 and 12 months were obtained for microbiological evaluation one time pre and post-operatively at intervals of 3,6,9, and 12 months.
• Radiographic periapical films pre as well as post-treatment at 3,6,9, and 12 month intervals to evaluate the bone formation at the intra- bony defects.
Results of the present study showed that:
1. Both CHLO-SITE gel and ATRIDOX gel delivered locally into periodontal diseased sites reduced all sub- gingival bacteria;
2. ATRIDOX gel demonstrated a faster release than CHLO-SITE gel ;
3. Both subgingival scaling and root planning alone and CHLO-SITE gel or ATRIDOX gel combined with scaling and root planning led to a highly statistically significant important in microbiological counts as well as clinical parameters applied. No clinical relevant side-effects more observed.