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Abstract Instillation of a 3 to 10ml bolus of normal saline prior to endotracheal suctioning is a traditional intervention performed by nurses. Little empirical evidence supports this nursing practice. The aim of the study was to determine the effect of using normal saline instillation on oxygenation for mechanically ventilated patients undergoing endotracheal suctioning. Materials and Method: A quasi-experimental research design was employed for this study. During August 2005 to April 2006, total thirty patients were selected from critical care units of the Menoufyia university hospital; each patient was suctioned 4 times: twice with and twice without instillation of normal saline. Two tools were used for data, collection: a) Clinical assessment sheet including: socio-demographic data, medical history, current lung condition and physical respiratory assessment b) Suction record sheet including suction data, characteristics of secretions, cardiovascular indicators, respiratory indicators, arterial blood gases and PaO2/ FiO2. Results: revealed that, (46.7%) of subjects aged between 50 - < 60 years, (53.3%) of them were males, and (36.6%) had technical work. The most frequent diagnosis (53.3%) was head injuries, all subjects (100%) were given antibiotics, (36.6%) were smokers, while only (10%) of them were conscious. There was a significantly higher incidence of heart rate, arrhythmias, respiratory rate, and peak inspiratory pressure with use of normal saline instillation. The PaO2, SaO2, PaCO2, and PaO2 / FiO2 results were better without use of normal saline instillation than with normal saline instillation. Conclusions and recommendations: instillation of normal saline solution during endotracheal tube suctioning was not beneficial in removing secretions or has any physiological benefits for the patient. It had detrimental effects on oxygen saturation, PaO2, PaCO2, and PaO2 /FiO2. It is recommended that the instillation of sodium chloride 0.9 % shouldn’t be used as a routine part of the suctioning procedure. |